What is Berodual?
Berodual is a combination inhaler of Boehringer Ingelheim, which contains two bronchial-extending active ingredients: beta-2-agonists Fenoterol and anticholinergic Ipratropium bromide.
The combination acts over two different mechanisms and is therefore more effective than any individual active substance alone. Berodual is frequently used in emergency intake in acute breathing, but can also be used for regular therapy.
Available as a dosing aerosol and as a solution for nebulisers.
Active Ingredients & Mechanism of Action
Active ingredient: Fenoterol, Ipratropiumbromid
Berodual has two mechanisms:
Fenoterol (Beta-2-agonist):
- Activates beta-2-receptors in bronchial muscles
- Fast bronchodilation (3-5 minutes)
- duration of action: 4-6 hours
- inhibits mast cell release
Ipratropium bromide (anticholinergic):
- Blocks muscarin receptors
- Bronchodilatation (15-30 minutes admission)
- duration of action: 4-6 hours
- Reduced mucus secretion
Synergy effect: The two active ingredients complement each other: Fenoterol acts quickly, Ipratropium strengthens and extends the action. Together, they are more effective than the sum of the individual effects.
Who is it suitable for?
Berodual is suitable for:
- Acute breathability in COPD
- Asthma extracts
- Demand therapy for obstructive respiratory diseases
- Before diagnostic procedures (bronchoscopy)
Advantages:
- Double effect over two mechanisms
- Fast action
- Effective as single active ingredients
- As a nebulizer solution for heavy seizures
Restrictions:
- No controller therapy at Asthma
- Contains no corticoid
- In asthma ICS is always necessary
Available Dosages
Dosieraerosol:
- 50 μg Fenoterol + 20 μg Ipratropium per stroke
- If necessary: 1-2 strokes
- For permanent therapy: 1-2 strokes 3x daily
- Maximum: 8 strokes per day
Inhalation solution:
- 0.5 ml (10 drops) = 250 μg Fenoterol + 500 μg Ipratropium
- Acute breathability: 1-2 ml (20-40 drops)
- Dilute with 0.9% NaCl to 3-4 ml
- 3-4x daily, more frequent (under medical supervision)
Berodual N dosing aerosol: propellant-free formulation having the same active substance content.
How to Take
Dosieraerosol: 1. Remove protective cap, shake spray Two. Deep exhalation 3. Closing mouthpiece with lips 4. Breathe slowly and deeply, spray Five. Keep breath 10 seconds 6. Breathe slowly 7. Wait 1-2 minutes at second stroke
Number: 1. Add droplets in nebulizer containers Two. Dilute 0.9% with NaCl (about 3-4 ml) 3. inhale 5-15 minutes 4. Normal breathing, occasionally deep breathing
In case of acute breathing: Immediately inhale 2 strokes, repeat after 5 minutes if necessary. In case of severe breath, call emergency doctor!
** Don't spray your eyes!
Contraindications
Do not apply at:
- Sensitivity to Fenoterol, Ipratropium or Atropine derivatives
- Hypertrophic obstructive cardiomyopathy
- Tachyarrhythmias
Preview at:
- Severe heart disease
- Recently suffered heart attack
- Untreated diabetes
- phenochromocytoma
- Engangle glaucoma
- Prostate hyperplasia
pregnant: Only with clear indication. Fenoterol can inhibit pain.
Style time: Probably safe for inhalative use.
Possible Side Effects
**
- Tremor (trembling)
- Mouth dryness
- Headaches
- Coughs
- Nervosity
Occasionally:
- Heart turf
- Heart palp
- Squeeze
- nausea
- Heiserkeit
Selten:
- Paradox bronchospasmus
- Engangle glaucoma (at eye contact)
- Hypokaliemia
- Allergic reactions
** Tremor and cardiac turf are typical beta-2-agonist side effects and usually harmless.
Interactions
Preview at:
- Betablockers – can eliminate Fenoterol action
- MAO inhibitors – enhanced cardiovascular effects
- Tricyclic antidepressants – enhanced heart action
- Other sympathomimetics – additive effects
- Corticoids, Diuretics – Hypokaliemia risk
Synergistic effect: With xanthines (theophylline) – can be desired, but be careful with side effects.
Frequently Asked Questions
Similar Medications
Is Berodual right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor. Read the package leaflet before use.