What is Canemes?
Canemes is a drug with the active ingredient Nabilon, a synthetic cannabinoid. It is structurally related to THC and acts similar to the endocannabinoid system.
Canemes is approved in Germany for the treatment of nausea and vomiting in chemotherapy if other antiemetics do not have sufficient effect.
It offers a standardized dosage in capsule form and is classified as a prescription drug.
Active Ingredients & Mechanism of Action
Active ingredient: Nabilon (synthetisches Cannabinoid)
Nabilon acts via the endocannabinoid system:
Active mechanism:
- Agonist on CB1 and CB2 receptors
- Inhibits the breaking centre in the brain
- Modulated pain perception
Effects:
- Strong antiemetic (against nausea)
- Easy to relieve pain
- Arousing appetite
- Anxiolytic (anxiolytic)
Pharmacokinetics:
- Good organic bioavailability
- Start of action: 1-2 hours
- Working time: 8-12 hours
Who is it suitable for?
Canemes is approved by:
- nausea and vomiting by chemotherapy (if standard antiemetics fail)
**Off-Label insert possible at:* *
- Chronic pain
- Spastic
- Lost appetite
Provisions:
- Other anti-emetics not sufficiently effective
- Medical regulation on BtM recipe
Not suitable:
- In severe psychiatric diseases
- In pregnancy and breastfeeding
- Under 18 years
Available Dosages
Available strength:
- 1 mg capsules
Dosing in chemotherapy:
- 1-2 mg twice a day
- First dose in the evening before chemotherapy
- Continue during chemotherapy
- Up to 48 hours after last chemotherapy dose
Maximum balances:
- 6 mg daily, divided into 3 single doses
Important: Individual dose determination under medical supervision.
How to Take
Intake:
- Swallow capsules with water
- Independent meals possible
- First dose in the evening before chemotherapy
**
- BtM recipe required
- No driving or operating machines
- No alcohol
- Regular medical checks
Contraindications
Notes:
- hypersensitivity to nabilone or cannabinoids
- Severe mental illnesses
- Pregnancy and breastfeeding
Preview at:
- cardiovascular diseases
- Liver disease
- Finding diseases in history
- Older patients
Possible Side Effects
**
- Squeeze
- Sleeping
- Mouth dryness
- euphoria
- Concentration disorders
Occasionally:
- visual disorders
- Heart turf
- Appetite changes
- mood swings
Selten:
- Hallucinations
- Paranoia
- Depression
Interactions
Reactions with:
- CNS-damping substances (benzodiazepines, opioids)
- Alcohol
- Anticholinergic
Commissioning:
- Driving and operating machines contraindicated
Frequently Asked Questions
Similar Medications
Is Canemes right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor. Read the package leaflet before use.