What is Ariline?
Arilin® vaginal cups contain the active ingredient Metronidazole and are used for the local (intravaginal) treatment of trichomoniasis and bacterial vagina. The vaginal tablets release the active substance directly at the infection site.
Trichomonad infections (Trichomoniasis) are caused by the parasite Trichomonas vaginalis and are among the most common sexually transmitted infections worldwide. They express themselves through bad smelling, greenish-yellow outflow, itching and burning.
**In the case of trichomoniasis, the systemic (oral) metronidazole therapy is generally preferred, since the partner must also be treated. Arilin® vaginal cups can be used in addition or in light cases.
Active Ingredients & Mechanism of Action
Active ingredient: Metronidazol (500 mg Vaginalzäpfchen)
Active mechanism:
- Metronidazole is activated in the cell of the parasite/bacterium to toxic metabolites
- These metabolites damage the DNA of the microorganism
- Strange fractures in the DNA lead to cell death
- Works against protozoa (trichomonas) and anaerobic bacteria
Local application:
- High concentration of active substance directly in the vagina
- Lower systemic intake than oral administration
- Partial systemic absorption (approximately 20–25% of dose)
Activity spectrum:
- Trichomonas vaginalis
- Gardnerella vaginalis
- Anaerobe bacteria (Bacteroides, Fusobacterium, Clostridium)
Who is it suitable for?
Arilin® vaginal cups are suitable for:
- Women with Trichomoniasis (as complementary local therapy)
- Bacterial vaginal
- Mixed infections of the vagina with anaerobic pathogens
Restriction:
- Trichomoniasis: Orale Metronidazole therapy is standard treatment
- Partner treatment possible only orally
- Vaginal cups alone are often not enough for Trichomoniasis
Not suitable:
- Sole therapy of trichomoniasis without oral treatment
- First third-party pregnancy
- hypersensitivity to metronidazole or nitroimidazole
Available Dosages
Trichomoniasis:
- 1 vaginal cups (500 mg) daily for 7–10 days
- Bringing in the evening before bed
Bacterial vagina:
- 1 vaginal cups (500 mg) daily for 7 days
**Alternative (Arilin® oral – Standard therapy Trichomoniasis):* *
- 2 g Metronidazole as a single dose oral (partner also!)
- Or 500 mg twice a day orally for 7 days
How to Take
Application vaginal cups: 1. Wash hands thoroughly Two. Comfortable back position 3. introduce vaginal cups deep into the vagina 4. possible evening before bedtime Five. Leave on overnight
Important notes:
- Do not use sexual intercourse or condoms of latex during treatment
- No alcohol during and 48 hours after therapy (Antabus effect!)
- Use slip insert (running out the cups possible)
- Continue treatment during menstruation
- Partners must be treated orally!
Contraindications
**Arilin® must not be used at:* *
- hypersensitivity to metronidazole or other nitroimidazoles
- First third-party pregnancy
- Heavy liver failure
- Severe blood image disorders
Preview at:
- Pregnancy (2/3rd trimester: only if necessary)
- breastfeeding (Metronidazole goes over to breast milk)
- Liver disease
- Neurological predisorders
Possible Side Effects
Family (1–10 %):
- Vaginal burning, itching
- Increased outflow
- Metallic taste in the mouth (also with vaginal use due to partial absorption)
** Occasionally (0.1-1 %):* *
- nausea
- Headaches
- stomach pain
- Dark urine (harmless)
Selten:
- Peripheral neuropathy (for long-term use)
- Allergic reactions
Antabus effect: At the same time alcohol consumption: nausea, vomiting, flushing, headaches. No alcohol during and 48 hours after treatment!
Frequently Asked Questions
Is Ariline right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor. Read the package leaflet before use.